The Best NFL Player Props for Week 18

Wagering on NFL player props in Week 18 could be your last chance to bet on your favorite players before the regular season ends. For over half the league, this weekend will be their last action until next season.
I discuss my favorite NFL prop bets in Week 18 below. In addition to highlighting my best player props for the week, I also tell you where to bet to ensure you get the most value out of your wagers in Week 18.
Best NFL Player Props Today
BetUS Sportsbook provided the following odds for these NFL Week 18 player props.
| Week 18 Game | NFL Player Prop | Prop Odds |
|---|---|---|
| Carolina Panthers vs. Tampa Bay Buccaneers | Jalen Coker anytime TD | +280 |
| Baltimore Ravens vs. Pittsburgh Steelers | Derrick Henry 2+ TDs | +300 |
| Seattle Seahawks vs. San Francisco 49ers | Christian McCaffrey 18+ carries | -162 |
| New Orleans Saints vs. Atlanta Falcons | Drake London under 59.5 receiving yards | -112 |
| Miami Dolphins vs. New England Patriots | Quinn Ewers over 0.5 interceptions | -154 |
| Indianapolis Colts vs. Houston Texans | Riley Leonard under 29.5 pass attempts | -114 |
| Los Angeles Chargers vs. Denver Broncos | Bo Nix over 1.5 passing TDs | +120 |
Jalen Coker Anytime TD (+280)
Carolina faces a must-win matchup this week against the Buccaneers. The good news for the Panthers is that they already beat the Bucs in Week 16, so they know what it takes to defeat Tampa Bay.
For Carolina to secure another upset win over Baker Mayfield and the Bucs, the Panthers must exploit the holes in Tampa Bay’s passing defense. With the Buccaneers focused on stopping rookie Tetairoa McMillan, the field should open up for Jalen Coker.
Coker only has 27 catches in the 10 games he has played this season, but he is second on the Panthers with 347 receiving yards. He also has two touchdown catches, tied for the fourth-most on the team.
Oddsmakers list Coker at +280 to score against the Bucs this weekend. Bryce Young must win this game with his arm, meaning more opportunities for Coker to make plays with the Bucs’ attention on McMillan.
Derrick Henry 2+ TDs (+300)
After a season’s worth of criticism and their season on the line, the Ravens finally turned to Derrick Henry in Weeks 16 and 17. Henry had 10 TDs in the first 14 games, but he has racked up six scores in the last two weeks.
King Henry’s 16 rushing scores this season are just one shy of the career-high 17 single-season rushing scores set in 2020.
Henry is listed at -167 to score once this weekend. With the Ravens’ season on the line against the Steelers, though, I expect Baltimore to continue to lean on Henry. He is available at +300 odds to score twice this week in Pittsburgh.
The Steelers kept Henry from scoring in their Week 14 matchup, but he did rack up 94 rushing yards. Pittsburgh’s defense has struggled at times to stop the run, including allowing over 210 yards on the ground to Baltimore in their last matchup.
With Lamar Jackson battling a back injury, Henry should get the ball early and often. A heavy workload will increase Henry’s odds of scoring multiple times this weekend.
Christian McCaffrey 18+ Carries (-162)
Speaking of workhorse running backs, Christian McCaffrey leads the NFL with 399 touches this season. He is second in scrimmage yards with 2,069 and leads the league with 20 touchdowns.
CMC should see another busy day this week against Seattle. He had 22 carries and nine receptions when the 49ers beat the Seahawks in Week 1. Controlling the clock through the running game will be especially important this week, given how explosive the Seahawks’ offense can be.
Multiple 49ers offensive stars, including OT Trent Williams (hamstring), TE George Kittle (ankle), and WR Ricky Pearsall (ankle/knee), are questionable. If Kittle or Pearsall are out, that will only increase CMC’s workload.
CMC has had at least 20 carries in nine games this season. He only needs 18 rush attempts to cover the over in this NFL Week 18 prop bet at -162 odds.
Drake London Under 59.5 Receiving Yards (-112)
Drake London returned in Week 16 after missing four games with a knee injury. In his two games back, London has just four catches for 31 yards.
In Monday’s upset win over the Rams, London only had one reception on two targets. He is healthy enough to play, but his knee injury is clearly still hindering the star wideout. London was limited in practice this week and should see a light workload at best this week against New Orleans.
Oddsmakers have London listed at over/under 59.5 receiving yards. London topped 60 receiving yards in five of his nine games before his injury. However, in every game this year, London has either exceeded 100 receiving yards or been held to 55 or fewer receiving yards.
I doubt the Falcons will feed London enough for him to rack up 60 receiving yards this week, especially in a meaningless Week 18 game when he has a knee injury. I recommend the under on this total receiving yards player prop.
Quinn Ewers Over 0.5 Interceptions (-154)
Rookie quarterback Quinn Ewers faces his toughest opponent in his final start of the season when he attempts to lead the Dolphins to an upset win over the Patriots. New England has an outside shot at the number one seed, so the Pats’ starters should play the majority of the game.
Ewers played the best game of his young career last week. He threw his first two TD passes and did not throw a pick in the team’s 20-17 win over the Buccaneers.
New England’s defense is significantly better than Tampa Bay’s. The Pats have only forced 17 takeaways, but New England also gives up just 302.4 YPG, the seventh-fewest in the league. They have also held opponents under 200 passing YPG this season.
The cold weather should also affect the Dolphins’ passing game this week. With that in mind, I think Ewers is a good bet to throw over 0.5 interceptions (-154) this week.
Riley Leonard Under 29.5 Pass Attempts (-114)
Another rookie QB starting this week is Riley Leonard. After three weeks of the Philip Rivers experiment, the Colts will turn to Leonard for the regular season finale. It will be Leonard’s first start in his NFL career.
Leonard could not have drawn a worse matchup to make his starting debut. Houston has one of the best defenses in the NFL, ranking at or near the top of the league in the following categories:
- 272.4 total YPG allowed (1st)
- 177.6 passing YPG allowed (4th)
- 16.6 PPG allowed (1st)
- 46 sacks (5th)
Leonard is listed at over/under 29.5 passing attempts for this week’s game. A 30+ attempt game for Leonard is the exact opposite of what Indy should try to do this week. The Colts must run the ball to take pressure off Leonard in the rookie’s first start against the league’s best passing defense.
The Colts’ offense has been at its best when running the ball with Jonathan Taylor. Finding room to run against the Texans has been easier said than done, and Houston only allows 94.8 rushing YPG this year. Still, the Colts should run the ball early and often, so Leonard will have under 29.5 attempts in his first career start.
Bo Nix Over 1.5 Passing TDs (+120)
Bo Nix and the Broncos can lock up the number one seed in the AFC with a win over the Chargers this week. Denver’s chances of securing the top seed increased significantly when LA announced Justin Herbert would not be in the starting lineup.
With Herbert on the sidelines, Trey Lance will take over starting QB duties for the Chargers.
We saw Denver in a similar spot last year against the Chiefs’ backups in Week 18. The Broncos blew out KC’s backups 38-0.
LA’s other available starters should play, but injuries have limited the Chargers to backups at many key positions. Sean Payton has a history of running up the score when he can, and Denver needs to build momentum ahead of the postseason.
The Broncos’ offense has struggled recently, so a big game against the Chargers could be precisely what Nix and company need. Nix is listed at +120 odds to throw for over 1.5 passing TDs this week, and he will cover.
What Are Your Week 18 NFL Player Prop Predictions?
Read the guide above to see my picks for the best NFL player props in Week 18. I break down my top seven player props for the final week of the season.
Then, sign up at BetUS to wager on your Week 18 NFL player props today. Every new member who makes a qualifying first deposit can claim a 225% welcome bonus worth up to $3,625 in extra funds. There is also a 75% re-up bonus for crypto depositors.
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