International NFL Games: Colts vs. Commanders Odds, Picks, and Analysis

Jonathan Taylor

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The international NFL games are moving to familiar territory for Week 4: London. The Colts and Commanders square off at Tottenham Hotspur Stadium this week, and Indianapolis is the betting favorite.

Continue reading for the latest odds on this 2026 NFL international series game. Also, I will break down my top picks for Colts vs. Commanders and explain my reasoning behind each prediction.

Current Indianapolis Colts vs. Washington Commanders London Odds Snapshot

Here are the latest Colts vs. Commanders odds, courtesy of the top NFL betting sites.

MarketLucky RebelBetUSBetOnline
MoneylineColts (-210) vs. Commanders (+175)Colts (-195) vs. Commanders (+167)Colts (-195) vs. Commanders (+170)
Point SpreadColts -4.0 (-110)Colts -3.5 (-110)Colts -4.0 (-110)
Total PointsOver/Under 47.5Over/Under 47.0Over/Under 47.0

The odds above were last checked on September 30th, 2026.

Indianapolis is a 3.5- to 4.0-point favorite for its trip across the pond against the Commanders. Washington is available as a moneyline underdog at +167 or longer odds.

Both teams are 1-2 after securing their first wins of the season last weekend. The odds could shift if and when QB Jayden Daniels’ playing status is officially announced. Daniels dislocated his elbow in Week 2 but is practicing this week.

Colts vs. Commanders Prop Wagers

Here are three of my top prop bets for Colts vs. Commanders in London.

  • Lucky Rebel: Jonathan Taylor anytime TD scorer (-305)
  • BetUS: Terry McLaurin 65+ receiving yards (+125)
  • BetOnline: Commanders over 2.5 TDs scored (+110)

Jonathan Taylor has the shortest odds of any player to score in this matchup at -305 at Lucky Rebel. Taylor has four rushing TDs this season, tied for the third-most in the NFL.

There are enticing props for the Commanders, too. BetUS lists Terry McLaurin at +125 odds to have 65+ receiving yards. BetOnline, on the other hand, has Washington available at +110 to score over 2.5 TDs as a team this week. 

The Nerd’s Verdict on Indianapolis Colts vs. Washington Commanders London

Here are my best picks for Week 4’s international game between the Colts and the Commanders.

Colts vs. Commanders Moneyline

Commanders Logo
  • Verdict: Bet the Commanders to win
  • Best captured price: +175 at Lucky Rebel
  • Break-even probability: 36.36%
  • Target price: +150 or longer odds
  • Primary risk: Jayden Daniels’ status is up in the air.
  • Confidence: Moderate – Marcus Mariota showed last week that he can run Washington’s offense effectively.

Washington Commanders (+175)

Washington knocked off the defending champion Seahawks last week, but they are +175 underdogs against the 1-2 Colts in London. Like Washington, Indianapolis is coming off its first win of the season, a 19-17 win over the Texans (0-3).

Jayden Daniels is questionable for this game, but I think the Commanders can win even if Daniels is out. The passing game is better with Mariota in the lineup, which makes the whole offense run more smoothly.

Daniels completed 29 of 51 attempts (56.9%) for 260 yards and three touchdowns in roughly six quarters of play. Over a similar span, Mariota has completed 30 of 47 attempts (63.8%) for 294 yards and four passing TDs.

Mariota does not have the rushing upside that Daniels offers, but he could be the better play against a Colts team that allows 276 passing yards per game (3rd most). I like this bet more if Mariota plays, but I still think Washington is the best bet to win if Daniels is under center.

Colts vs. Commanders Point Spread

Washington Commanders quarterback Jayden Daniels
  • Verdict: Bet the Commanders to cover
  • Best captured price: +4.0 (-110) at BetOnline
  • Break-even probability: 52.38%
  • Target price: +3.0 or more
  • Primary risk: Washington’s pass defense has allowed the second-most yards in the league this year.
  • Confidence: Moderate – Indianapolis is without its best WR and has struggled to pass the ball this year.

Washington Commanders +4.0 (-110)

Indianapolis is favored for the first time this season, but I do not think they will cover. As mentioned above, I believe the Commanders are the better bet to win this game. However, even if the Colts do win, I doubt it will be by more than a field goal.

The Colts are still without WR Alec Pierce (IR – Heel), and Daniel Jones is averaging just 203.7 passing YPG (23rd).

Jonathan Taylor has done his best in the running game to make up for the lack of a passing attack. Taylor faces a tough run defense this week, though. Washington’s run defense ranks third in the league, allowing just 82.0 YPG on the ground.

Stifling Taylor will be easier said than done, but it is the key to Washington’s chances at covering the 4.0-point spread this weekend.

Indy’s poor passing defense should help Washington slow down Taylor. If the Commanders can score early and often, they will limit Taylor’s rushing opportunities and overall production.

Best Colts vs. Commanders Player Prop

WR Terry McLaurin
  • Verdict: Bet on Terry McLaurin 65+ yards
  • Best captured price: +125 at BetUS
  • Break-even probability: 44.44%
  • Target price: -125 or longer odds
  • Primary risk: McLaurin struggled to connect with Daniels earlier this season.
  • Confidence: Moderate – McLaurin averages 71.5 receiving YPG with Marcus Mariota as his QB.

Terry McLaurin 65+ Receiving Yards (+125)

BetUS has WR Terry McLaurin listed at +125 odds to have 65+ receiving yards against the Colts this weekend.

McLaurin started slowly, catching just four of his 13 targets in the first two weeks. He had a much better game in Week3, catching six of nine targets for 77 yards. He averages 71.5 receiving YPG with Marcus Mariota as his QB.

The Colts are an ideal matchup for any struggling passing offense. Indy has allowed 276 passing YPG, the third-most. Against receivers specifically, the Colts are allowing 16.81 yards per reception this year.

Indianapolis has also allowed nine 20+ yard plays to WRs this year, including four 40+ yard plays. A handful of catches against one of the league’s worst passing defenses is all McLaurin needs to cover this player prop.

Who the Market Picks to Win: Colts vs. Commanders

The market is favoring the Colts this weekend in London. Indy has the best player, Jonathan Taylor, but that does not make them the better team. A major part of the current odds is Jayden Daniels’ injury status.

Daniels dislocated his elbow in Week 2 and missed last week’s game. However, Marcus Mariota has proven to be one of the better backups in the NFL since joining the Commanders.

Last week, Mariota picked apart one of the best defenses in the league, the Seahawks. Indianapolis has a much weaker pass defense, so Mariota should be able to build on his performance from last week if he is in the lineup.

A limited Daniels is a different story, especially if he cannot scramble as much as he is used to. Daniels has completed over 65% of his passes in his career and can pull off an upset if he takes advantage of the Colts’ porous pass defense.

3 Biggest Factors That Can Influence Colts vs. Commanders

Here are the three biggest factors to consider when betting on 2026 NFL international games this week.

Commanders Logo

Jayden Daniels Injury

The biggest question for Washington this weekend is whether Jayden Daniels will play. Daniels returned to practice this week, but he is questionable to play in London. Having Daniels in the lineup can drastically change the Commanders’ offense. Expect the line to shift toward Washington if Daniels is cleared to start on Sunday.

jonathan taylor

Jonathan Taylor vs. Washington’s Run Defense

Jonathan Taylor has been the engine for the Colts’ offense once again this season. He is 10th in the NFL with 325 yards from scrimmage this year. Taylor is one of the best running backs in the NFL, with 258 rushing yards and four rushing scores this season. However, he faces a tough Commanders’ defense that has allowed fewer than 250 rushing yards this year. If Washington shuts down Taylor, the whole Colts’ offense will stall.

Colts Logo

The Colts’ Special Teams

The Colts’ special teams are also worth watching this weekend. Kicker Spencer Shrader hurt his groin in warm-ups last week. Despite the injury, Shrader hit all four of his field goal attempts and a PAT in last week’s win. Indy had punter Rigoberto Sanchez handle kickoff duties, and he may be tasked with them again this week. Also, if the international travel aggravates Shrader’s injury at all, the Colts kicking game could be limited.

International NFL Games 2026 Predictions

Indianapolis is a moderate favorite this weekend, but I think Washington can pull off the upset in London. The Colts’ passing defense is simply too porous to back them as a favorite this weekend.

(Photo by AP Photo/Zach Bolinger)

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About the Author

Shaun Stack, a native of the state of Kansas, has been a lifelong fan of all sports. Shaun has a Bachelor of Science in Psychology from the University of Pittsburgh Bradford. He has been writing for Gambling Nerd for several years, covering a wide range of topics.