• NFL

NFL Week 15 Predictions and Best Bets

There are 16 thrilling matchups to pick from for your NFL Week 15 predictions. With bye weeks a thing of the past, every team will be taking the field this week, with many fighting for their playoff lives. 

Keep reading to see the updated betting lines and my NFL prediction in Week 15. I give my picks for every game and highlight my favorite bets of the weekend.

NFL Week 15 Overview

BetOnline provided the following odds for NFL Week 15. 

• Atlanta Falcons vs. Tampa Bay Buccaneers -4.0 (-115)
• Cleveland Browns vs. Chicago Bears -7.5 (-110)
• Baltimore Ravens -2.5 (-114) vs. Cincinnati Bengals
• Arizona Cardinals vs. Houston Texans -9.5 (-115)
• New York Jets vs. Jacksonville Jaguars -12.0 (-115)
• Los Angeles Chargers vs. Kansas City Chiefs -4.0 (-117)
• Buffalo Bills PK (-115) vs. New England Patriots 
• Washington Commanders vs. New York Giants -2.0 (-110)
• Las Vegas Raiders vs. Philadelphia Eagles -10.5 (-110)
• Green Bay Packers -2.0 (-115) vs. Denver Broncos
• Detroit Lions vs. Los Angeles Rams -6.0 (-110)
• Carolina Panthers -2.5 (-118) vs. New Orleans Saints 
• Indianapolis Colts vs. Seattle Seahawks -13.5 (-110)
• Tennessee Titans vs. San Francisco 49ers -13.0 (-104)
• Minnesota Vikings vs. Dallas Cowboys -5.5 (-110)
• Miami Dolphins vs. Pittsburgh Steelers -3.5 (-106)

Top NFL Week 15 Games to Watch

Here are my top five games for Week 15. 

• Baltimore Ravens -2.5 (-114) vs. Cincinnati Bengals
• Buffalo Bills PK (-115) vs. New England Patriots 
• Green Bay Packers -2.0 (-115) vs. Denver Broncos
• Detroit Lions vs. Los Angeles Rams -6.0 (-110)
• Minnesota Vikings vs. Dallas Cowboys -5.5 (-110)

NFL Week 15 Predictions 2025

Let’s take a closer look at my best Week 15 NFL predictions, using odds from the top NFL betting sites. 

Baltimore Ravens -2.5 (-114) vs. Cincinnati Bengals

Team	Point Spread	Moneyline	Total
Baltimore Ravens	-2.5 (-114)	-142	Over 51.5 (-105)
Cincinnati Bengals	+2.5 (-106)	+122	Under 51.5 (-115)

Baltimore, which had won five straight games, has dropped back-to-back matchups against divisional opponents. On the bright side, the Ravens have a chance to even their season series with the Bengals this weekend. 

The Ravens are 2.5-point road favorites in this AFC North clash. 

Cincy’s playoff hopes suffered a serious blow after their 39-34 loss in Buffalo last week. The Bengals’ only hope of making the postseason now is to win the division. Sweeping the Ravens this weekend would go a long way toward helping the Bengals win the North. 

When these teams met on Thanksgiving, Baltimore’s defense could not stop Burrow and company. The Ravens’ offense also looked stagnant. However, Lamar Jackson looked healthier last week, scoring his first rushing touchdown since Week 1. 

Jackson’s rushing ability could be the deciding factor in this game. No team allows more rushing yards than the Bengals, who give up over 155 rushing YPG. If Baltimore fully commits to the run, they will win and cover this weekend. 

Buffalo Bills PK (-115) vs. New England Patriots 

Team	Point Spread	Moneyline	Total
Team	Point Spread	Moneyline	Total
Buffalo Bills	PK (-115)	N/A	Over 49.5 (-110)
New England Patriots	PK (-105)	N/A	Under 49.5 (-110)

All eyes have been on this Week 15 matchup between the Bills and the Patriots after New England upset Buffalo on SNF in Week 5. Since that game, the Pats have won eight consecutive games, extending their winning streak to 10 games. 

New England is the home team for the rematch, but that has done the Pats few favors in the eyes of the oddsmakers. This game is a pick’em, with the odds leaning slightly toward Buffalo (-115) over New England (-105). 

A win this weekend would clinch the AFC East for the Patriots. Winning will be easier said than done, though, as Josh Allen has been playing at a superhuman level lately. 

On the other hand, the Pats’ defense largely contained Allen in Week 5, forcing the pressure onto the Bills’ subpar receiving corps to make plays. They could not, and it led to the Bills’ first loss of the season. It should be a similar outcome this weekend, with New England pulling off the division-sealing win. 

Green Bay Packers -2.0 (-115) vs. Denver Broncos

Team	Point Spread	Moneyline	Total
Green Bay Packers	-2.0 (-115)	-137	Over 43.5 (-110)
Denver Broncos	+2.0 (-105)	+117	Under 43.5 (-110)

Another must-see matchup this weekend pits the Packers (9-3-1) against the Broncos(11-2) in Denver. The Broncos’ 10-game winning streak is tied with the Patriots for the longest active streak in the NFL. 

Denver’s defense has been the driving force behind its success this year. The Broncos lead the NFL with 55 sacks. They are also third in yards allowed, giving up 282 YPG, and fourth in points, allowing 18.1 PPG. 

Despite their impressive defense, the Broncos are home underdogs this weekend against the visiting Packers. Green Bay is laying 2.0 points at Mile High in this battle of division leaders. 

The Packers’ defense has also been impressive this season, surrendering 287.2 YPG (5th), 19.0 PPG (6th), and generating 33 sacks (T11th). 

Both teams’ offenses have struggled this year, and that could be the defining feature in this game. Denver’s -3 turnover differential could finally catch up with them against another top defense in the league. Green Bay wins and covers as Jordan Love’s Toyotathon legend grows. 

Detroit Lions vs. Los Angeles Rams -6.0 (-110)

Team	Point Spread	Moneyline	Total
Detroit Lions	+6.0 (-110)	+226	Over 55.0 (-105)
Los Angeles Rams	-6.0 (-110)	-275	Under 55.0 (-115)

The Lions (8-5) and the Rams (10-3) also square off this weekend. Including the playoffs, this is the fourth time Detroit and LA have faced off since swapping QBs in 2021. 

So far, Jared Goff and the Lions have the edge 2-1 over Matthew Stafford and the Rams. However, LA is the 6.0-point home favorite heading into this week’s game. 

Detroit is 3-3 on the road this season. The Rams, on the other hand, are 5-1 as a home team this far. Los Angeles also has a +152 point differential this year, the second-highest in the league so far. 

The Lions’ point differential is also impressive at +90, but their offense has struggled at times. Detroit has been held under 20 points in three of its five losses this year. Goff has struggled with pressure throughout his career, and this season has been no different. 

Harassing Goff is the key to slowing down the Lions’ high-flying offense. LA’s defense is tied for sixth with 36 sacks, one fewer than the Lions. Detroit’s struggling o-line and their injury-riddled defense will be their fatal flaws this week in SoFi. 

Minnesota Vikings vs. Dallas Cowboys -5.5 (-110)

Team	Point Spread	Moneyline	Total
Minnesota Vikings	+5.5 (-110)	+222	Over 47.5 (-110)
Dallas Cowboys	-5.5 (-110)	-270	Under 47.5 (-110)

The final spot on my NFL predictions for Week 15 is the Sunday Night Football showdown between the Cowboys (6-6-1) and the Vikings (5-8). Neither team has been officially eliminated from the playoffs, but a loss this weekend would effectively end either team’s season. 

Dallas lost on TNF last week, falling 44-30 against the Lions in Detroit. Despite a poor defensive showing last week, the Cowboys are 5.5-point home favorites for this prime-time game. 

The Cowboys have been a tough out at home, averaging over 34 PPG en route to a 4-1-1 record at Jerry’s World. However, they are also just 3-5-1 against NFC opponents this season and have a -5 point differential. 

Three of the Vikings’ five wins have been on the road. Minnesota is coming off an impressive 31-0 win over the Commanders that also ended a four-game losing streak. 

Their inconsistent offense makes it challenging to trust the Vikings to pull off the upset. However, I do think they can cover the 5.5-point spread in prime time this weekend against a shaky Dallas defense. 

More NFL Week 15 Picks & Predictions

Matchup	Week 15 NFL Prediction
Atlanta Falcons vs. Tampa Bay Buccaneers -4.0 (-115)	Tampa Bay Buccaneers (-230)
Cleveland Browns vs. Chicago Bears -7.5 (-110)	Chicago Bears -7.5 (-110)
Arizona Cardinals vs. Houston Texans -9.5 (-115)	Arizona Cardinals +9.5 (-105)
New York Jets vs. Jacksonville Jaguars -12.0 (-115)	Jacksonville Jaguars -12.0 (-115)
Los Angeles Chargers vs. Kansas City Chiefs -4.0 (-117)	Kansas City Chiefs (-225)
Washington Commanders vs. New York Giants -2.0 (-110)	Washington Commanders (+110)
Las Vegas Raiders vs. Philadelphia Eagles -10.5 (-110)	Las Vegas Raiders +10.5 (-110)
Carolina Panthers -2.5 (-118) vs. New Orleans Saints	Carolina Panthers -2.5 (-118)
Indianapolis Colts vs. Seattle Seahawks -13.5 (-110)	Seattle Seahawks -13.5 (-110)
Tennessee Titans vs. San Francisco 49ers -13.0 (-104)	Tennessee Titans +13.0 (-116)
Miami Dolphins vs. Pittsburgh Steelers -3.5 (-106)	Miami Dolphins (+163)

Explore all our 2025 NFL Season Predictions. It’s also getting close to the postseason, so start thinking about which teams you’re slotting into your NFL playoff bracket!

Where to Bet on Your NFL Week 15 Predictions

BetOnline is the top place to bet on your NFL Week 15 predictions. It provides competitive odds for all 16 games on this week’s schedule. Also, as a new member, you can get a 50% bonus worth up to $250 in free bets for this week’s matchups when using the code FREE250 while making your first deposit.